Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111396 | 0.79 | SLC22A2 (0.50) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4027679 | 0.77 | SLC22A2 (0.48) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL27740239 | 0.75 | SLC22A2 (0.48) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL40513 | 0.72 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8344710 | 0.72 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL182779 | 0.72 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14306348 | 0.72 | SLC22A2 (0.44) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL25492074 | 0.69 | MAPT (0.57) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL19758138 | 0.69 | SMN1; SMN2 (0.53) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5711911 | 0.69 | SLC22A2 (0.46) | SLC22A2SLC47A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712599-A | Novel sulfonic acid derivative compound and novel naphthalic acid derivative compound | ADEKA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-100577651-C | Lactam compound and medicinal use thereof | AJINOMOTO KK | 2010-01-06 | — | — | CN | disclosed |
| CN-1911915-A | Lactam compound and medicinal use thereof | AJINOMOTO KK (JP) | 2007-02-14 | — | — | CN | disclosed |
| CN-1269818-C | Lactam compounds and pharmaceutical use thereof | AJINOMOTO KK (JP) | 2006-08-16 | — | — | CN | disclosed |
| CN-1487940-A | Lactam compounds and pharmaceutical use thereof | ֮����ʽ���� | 2004-04-07 | — | — | CN | disclosed |