Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | HPN | P05981 | 2/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413216 | 0.77 | MMP3 (0.65) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL6414008 | 0.77 | MMP3 (0.65) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL6413210 | 0.77 | MMP3 (0.65) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL8341471 | 0.76 | MMP3 (0.50) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL4431378 | 0.74 | MMP3 (0.70) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL6419780 | 0.74 | MMP3 (0.67) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL6419785 | 0.74 | MMP3 (0.67) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL4431389 | 0.74 | MMP3 (0.70) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL6418278 | 0.74 | MMP3 (0.70) | MMP3MMP2MMP9ADAMTS4HPN | |
| SCHEMBL8340680 | 0.72 | MMP3 (0.57) | MMP3MMP2MMP9ADAMTS4HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |