Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 13/20 | 0.49 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.41 |
| ▸ | INPP5B | P32019 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344276 | 0.94 | ALOX15 (0.64) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8346627 | 0.92 | ALOX15 (0.62) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8346532 | 0.81 | ALOX15 (0.55) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8480850 | 0.80 | SRC (0.53) | INPPL1INPP5AINPP5BSRCAKT1 | |
| SCHEMBL29145019 | 0.80 | INPPL1 (0.42) | MAPTALOX15INPPL1INPP5AINPP5B | |
| Probucol SCHEMBL8344272 | 0.77 | HPN (0.81) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL27456035 | 0.75 | INPPL1 (0.38) | MAPTALOX15INPPL1INPP5AINPP5B | |
| Phosphoric Acid SCHEMBL27740009 | 0.75 | HSPA5 (0.44) | MAPTINPPL1INPP5AINPP5BSRC | |
| SCHEMBL11364581 | 0.74 | INPPL1 (0.53) | INPPL1INPP5AINPP5BSRCAKT1 | |
| SCHEMBL14598537 | 0.74 | HPN (0.57) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999024400-A1 | PROBUCOL ESTERS AND USES THEREOF | VYREX CORPORATION (US) | 1999-05-20 | — | — | WO | disclosed |