Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345257 | 0.87 | GRIN2D (0.38) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8342149 | 0.85 | GRIK1 (0.38) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8346054 | 0.84 | AR (0.36) | PARP1GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8344983 | 0.83 | CA12 (0.40) | CA12CA9PARP1GRIK1GRIK2 | |
| SCHEMBL8342333 | 0.81 | CA12 (0.46) | CA12CA9PARP1GRIK1GRIK2 | |
| SCHEMBL8342041 | 0.81 | AR (0.38) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8340485 | 0.80 | GRIA1 (0.36) | PARP1GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8345084 | 0.79 | GRIA1 (0.37) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8343002 | 0.79 | MAPT (0.41) | ALDH1A1MAPTLMNAGAA | |
| SCHEMBL8345478 | 0.78 | GRIK1 (0.54) | GRIK1GRIK2GRIK3GRIK4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |