Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 7/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342041 | 0.86 | AR (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8346054 | 0.83 | AR (0.36) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8344977 | 0.80 | CA12 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8345084 | 0.79 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8345710 | 0.76 | GRIA1 (0.31) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8124492 | 0.75 | AR (0.40) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8346146 | 0.73 | PGR (0.40) | — | |
| SCHEMBL8343157 | 0.73 | DAO (0.37) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8345257 | 0.71 | GRIN2D (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8342149 | 0.71 | GRIK1 (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |