Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772242 | 0.87 | CYP2C9 (0.46) | CYP2C9PKMEPHX2HSD11B1HSD11B2 | |
| Adamantan-2-Ol SCHEMBL9228492 | 0.84 | CYP2C9 (0.46) | CYP2C9EPHX2HSD11B1HSD11B2TSHR | |
| Adamantane SCHEMBL8487115 | 0.84 | PKM (0.46) | CYP2C9PKMEPHX2HSD11B1LMNA | |
| SCHEMBL12837800 | 0.82 | CYP2C9 (0.39) | CYP2C9PKMEPHX2HSD11B1HSD11B2 | |
| SCHEMBL23333268 | 0.81 | PKM (0.48) | PKMEPHX2LMNASLC22A2SLC22A1 | |
| SCHEMBL148421 | 0.81 | PKM (0.48) | PKMEPHX2LMNASLC22A2SLC22A1 | |
| SCHEMBL1150449 | 0.81 | PKM (0.48) | PKMEPHX2LMNASLC22A2SLC22A1 | |
| SCHEMBL2126658 | 0.81 | PKM (0.48) | PKMEPHX2LMNASLC22A2SLC22A1 | |
| Adamantan-2-Ol SCHEMBL350390 | 0.81 | CYP2C9 (1.00) | CYP2C9EPHX2HSD11B1SIGMAR1 | |
| Adamantan-2-Ol SCHEMBL8931261 | 0.81 | CYP2C9 (1.00) | CYP2C9EPHX2HSD11B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012572-A1 | COMPOUNDS AND METHOD FOR THE PREVENTION AND TREATMENT OF DIABETIC RETINOPATHY | UNIVERSITY OF FLORIDA (US) | 1999-03-18 | — | — | WO | disclosed |
| EP-0661986-A4 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM. | UNIV FLORIDA (US) | 1997-04-23 | — | — | EP | disclosed |
| EP-0661986-A1 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM | UNIVERSITY OF FLORIDA (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994006450-A1 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM | UNIVERSTIY OF FLORIDA (US) | 1994-03-31 | — | — | WO | disclosed |