Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.44 |
| ▸ | F2 | P00734 | 15/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344277 | 1.00 | PRSS1 (0.44) | PRSS1F2DPP4DPP8 | |
| SCHEMBL8345660 | 0.92 | PRSS1 (0.43) | PRSS1F2DPP4DPP8 | |
| SCHEMBL8345820 | 0.89 | PRSS1 (0.54) | PRSS1F2 | |
| SCHEMBL8340036 | 0.88 | PRSS1 (0.55) | PRSS1F2 | |
| SCHEMBL8342304 | 0.88 | PRSS1 (0.55) | PRSS1F2 | |
| SCHEMBL8345139 | 0.88 | PRSS1 (0.55) | PRSS1F2 | |
| SCHEMBL8345545 | 0.88 | PRSS1 (0.55) | PRSS1F2 | |
| SCHEMBL8339855 | 0.88 | PRSS1 (0.55) | PRSS1F2 | |
| SCHEMBL8341977 | 0.88 | PRSS1 (0.57) | PRSS1F2 | |
| SCHEMBL8346928 | 0.87 | PRSS1 (0.55) | PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |