Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343056 | 0.80 | MEN1 (0.35) | ALOX12ENPP2MAPTTP53ALOX5 | |
| SCHEMBL6969170 | 0.76 | MEN1 (0.41) | ALOX12AKR1B1PTGDR2ENPP2MAPT | |
| SCHEMBL8345201 | 0.75 | AKR1B1 (0.43) | AKR1B1PTGDR2ENPP2MAPTTP53 | |
| SCHEMBL6961690 | 0.74 | PTGDR2 (0.42) | AKR1B1PTGDR2ENPP2MAPTTP53 | |
| SCHEMBL6973394 | 0.72 | MEN1 (0.42) | AKR1B1PTGDR2MAPTPOLBMEN1 | |
| SCHEMBL6966777 | 0.71 | MEN1 (0.46) | AKR1B1PTGDR2MAPTPOLBMEN1 | |
| SCHEMBL8349460 | 0.68 | ALOX12 (0.34) | ALOX12MAPTTP53POLBSLC6A9 | |
| SCHEMBL6975073 | 0.68 | MEN1 (0.46) | AKR1B1PTGDR2MAPTPOLBMEN1 | |
| SCHEMBL6968122 | 0.67 | MEN1 (0.36) | ALOX12ENPP2MAPTTP53MEN1 | |
| SCHEMBL8345418 | 0.66 | MAPT (0.34) | MAPTTP53MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |