Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296415 | 0.90 | SMN1; SMN2 (0.44) | LMNAALDH1A1ALOX5 | |
| SCHEMBL8014867 | 0.85 | FFAR1 (0.50) | ALDH1A1FFAR1FFAR4LTB4RLTB4R2 | |
| SCHEMBL8008297 | 0.84 | FFAR1 (0.57) | LMNAL3MBTL1FFAR1FFAR4LTB4R | |
| SCHEMBL8343697 | 0.84 | FFAR1 (0.57) | LMNAL3MBTL1FFAR1FFAR4LTB4R | |
| SCHEMBL8008244 | 0.82 | FFAR1 (0.49) | LMNAL3MBTL1FFAR1FFAR4LTB4R | |
| SCHEMBL6297746 | 0.82 | CYP4F2 (0.38) | LMNAALDH1A1PPARG | |
| SCHEMBL3744601 | 0.80 | FFAR1 (0.62) | LMNAL3MBTL1NR1H4ALDH1A1FFAR1 | |
| SCHEMBL6297611 | 0.80 | PPARG (0.40) | ALDH1A1PPARG | |
| SCHEMBL7636702 | 0.79 | PPID (0.49) | LMNAALDH1A1 | |
| SCHEMBL7636689 | 0.79 | PPID (0.49) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014210-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRAN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-03-25 | — | — | WO | claimed |
| WO-1999014210-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRAN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |