Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762765 | 1.00 | CAPN1 (0.72) | CAPN1CYP2D6MAPTMEN1KMT2A | |
| SCHEMBL7762773 | 1.00 | CAPN1 (0.72) | CAPN1CYP2D6MAPTMEN1KMT2A | |
| SCHEMBL7209524 | 0.88 | CAPN1 (0.59) | CAPN1 | |
| SCHEMBL7209529 | 0.88 | CAPN1 (0.59) | CAPN1 | |
| SCHEMBL7763979 | 0.85 | CAPN1 (0.77) | CAPN1CYP2D6MAPTMEN1KMT2A | |
| SCHEMBL7762727 | 0.85 | FCER2 (0.56) | CAPN1 | |
| SCHEMBL7762736 | 0.85 | FCER2 (0.56) | CAPN1 | |
| SCHEMBL8344939 | 0.85 | FCER2 (0.56) | CAPN1 | |
| SCHEMBL16445069 | 0.84 | CAPN1 (1.00) | CAPN1MAPTCYP3A4CYP2C19LMNA | |
| SCHEMBL7765729 | 0.83 | CAPN1 (0.52) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |