Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202933 | 0.91 | CAPN1 (0.64) | CAPN1MMP1LMNACTSLCTSB | |
| SCHEMBL7406064 | 0.88 | CAPN1 (0.61) | CAPN1KMT2ALMNACTSLCTSB | |
| SCHEMBL11667610 | 0.88 | CAPN1 (0.61) | CAPN1LMNACTSLCTSBCTSG | |
| SCHEMBL7765666 | 0.87 | CAPN1 (0.59) | CAPN1MMP1LMNACTSLCTSB | |
| SCHEMBL16445098 | 0.87 | CAPN1 (1.00) | CAPN1LMNACTSLCTSBCTSG | |
| SCHEMBL7761860 | 0.86 | CAPN1 (0.58) | CAPN1LMNACTSLCTSBCTSG | |
| SCHEMBL9088985 | 0.85 | CAPN1 (0.57) | CAPN1LMNACTSLCTSBCTSG | |
| SCHEMBL7761900 | 0.85 | CAPN1 (0.59) | CAPN1MMP1LMNACTSLCTSB | |
| SCHEMBL7762766 | 0.85 | CTSL (0.60) | CAPN1KMT2ALMNACTSLCTSB | |
| SCHEMBL7765662 | 0.85 | CTSL (0.60) | CAPN1KMT2ALMNACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |