Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.34 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342152 | 0.96 | GRIK1 (0.36) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8344983 | 0.88 | CA12 (0.40) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8340503 | 0.85 | GRIN1 (0.37) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8343007 | 0.84 | HTT (0.39) | — | |
| SCHEMBL8340390 | 0.83 | GRIA1 (0.43) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8340372 | 0.83 | HTT (0.39) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8345257 | 0.82 | GRIN2D (0.38) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8345473 | 0.82 | SLC22A6 (0.51) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8340567 | 0.81 | GRIN1 (0.39) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8346034 | 0.80 | SLC22A6 (0.56) | GRIK1GRIK2GRIK3GRIK4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |