Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340567 | 0.95 | GRIN1 (0.39) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8345260 | 0.85 | GRIK1 (0.34) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8345257 | 0.84 | GRIN2D (0.38) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8342205 | 0.81 | ALDH1A1 (0.40) | LMNACYP1A2CYP3A4MAPT | |
| SCHEMBL8342152 | 0.81 | GRIK1 (0.36) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8342149 | 0.80 | GRIK1 (0.38) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8108014 | 0.79 | ALDH1A1 (0.40) | LMNACYP1A2CYP3A4MAPT | |
| SCHEMBL8342195 | 0.79 | GRIA1 (0.58) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7357704 | 0.79 | GRIA1 (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8346030 | 0.79 | GRIK1 (0.59) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |