Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844351 | 0.85 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL5843954 | 0.80 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5845230 | 0.79 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL5789078 | 0.73 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5844119 | 0.71 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5845841 | 0.71 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5844541 | 0.69 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5845092 | 0.69 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL7476102 | 0.68 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL5843917 | 0.68 | CRHR1 (0.58) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962479-A | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 1999-10-05 | — | — | US | disclosed |