Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734690 | 0.75 | MAPK1 (0.30) | — | |
| SCHEMBL17635673 | 0.73 | — | — | |
| SCHEMBL17853993 | 0.72 | — | — | |
| SCHEMBL10522028 | 0.63 | TSHR (0.32) | — | |
| SCHEMBL23342976 | 0.62 | TP53 (0.30) | — | |
| SCHEMBL7363898 | 0.62 | TP53 (0.32) | MAPT | |
| SCHEMBL7356915 | 0.62 | TP53 (0.32) | MAPT | |
| SCHEMBL17917642 | 0.60 | CTSV (0.30) | — | |
| SCHEMBL17917654 | 0.60 | CTSV (0.30) | — | |
| SCHEMBL23846721 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948693-A | COVALENTLY BONDING SIDE CHAIN OF SELECTED AMINO ACID TO SOLID SUPPORT VIA ACID-LABILE OR PHOTO-LABILE LINKER, PROTECTING C-TERMINUS, SYNTHESIZING POLYPEPTIDE ON N-TERMINUS, DEPROTECTING C-TERMINUS AND CYCLIZING POLYPEPTIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998046247-A1 | SOLID PHASE SYNTHESIS OF IMMUNOSUPPRESSIVE AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0778847-A4 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RES FOUND (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0778847-A1 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5639852-A | ANALOGS OF CYCLOSPORIN A | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1996006857-A1 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-03-07 | — | — | WO | disclosed |