Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640779 | 0.89 | CASP3 (0.42) | CASP3KMT2AMDM4TP53PTPN1 | |
| SCHEMBL24579343 | 0.89 | CASP3 (0.42) | CASP3KMT2AMDM4TP53PTPN1 | |
| SCHEMBL26605892 | 0.86 | KMT2A (0.38) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL24579341 | 0.86 | KMT2A (0.38) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL29697697 | 0.86 | KMT2A (0.38) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL24579340 | 0.86 | KMT2A (0.38) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL29696614 | 0.86 | KMT2A (0.38) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL29670125 | 0.83 | CASP3 (0.52) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL24414058 | 0.82 | CASP3 (0.49) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL30902834 | 0.82 | CASP3 (0.49) | CASP3KMT2AMDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948693-A | COVALENTLY BONDING SIDE CHAIN OF SELECTED AMINO ACID TO SOLID SUPPORT VIA ACID-LABILE OR PHOTO-LABILE LINKER, PROTECTING C-TERMINUS, SYNTHESIZING POLYPEPTIDE ON N-TERMINUS, DEPROTECTING C-TERMINUS AND CYCLIZING POLYPEPTIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-09-07 | — | — | US | disclosed |