Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HTR4 | Q13639 | 12/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767167 | 0.90 | KCNH2 (0.62) | KCNH2HTR4HTR3A | |
| SCHEMBL5889439 | 0.88 | KCNH2 (0.61) | KCNH2HTR4HTR3A | |
| SCHEMBL6180780 | 0.87 | KCNH2 (0.60) | KCNH2HTR4HTR3A | |
| Hydrochloric Acid SCHEMBL6770784 | 0.87 | KCNH2 (0.59) | KCNH2HTR4HTR3A | |
| SCHEMBL6247389 | 0.86 | KCNH2 (0.68) | KCNH2HTR4HTR3A | |
| SCHEMBL5889899 | 0.86 | KCNH2 (0.62) | KCNH2HTR4HTR3ADRD2DRD4 | |
| SCHEMBL6703255 | 0.86 | KCNH2 (0.58) | KCNH2HTR4HTR3A | |
| SCHEMBL6306544 | 0.85 | KCNH2 (0.61) | KCNH2HTR4HTR3A | |
| SCHEMBL6306539 | 0.85 | KCNH2 (0.61) | KCNH2HTR4HTR3ADRD2DRD4 | |
| SCHEMBL7240727 | 0.85 | KCNH2 (0.60) | KCNH2HTR4HTR3ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026869-A1 | IMIDAZOPYRIDINE COMPUNDS AS 5-HT4 RECEPTOR AGONISTS | PFIZER JAPAN INC. (JP) | 2004-04-01 | — | — | WO | disclosed |