Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | HTR4 | Q13639 | 13/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240727 | 0.86 | KCNH2 (0.60) | KCNH2HTR4HTR3A | |
| SCHEMBL6247389 | 0.85 | KCNH2 (0.68) | KCNH2HTR4HTR3ACACNA1I | |
| SCHEMBL8345408 | 0.85 | KCNH2 (0.68) | KCNH2HTR4HTR3A | |
| SCHEMBL6314559 | 0.84 | KCNH2 (0.64) | KCNH2HTR4HTR3ACACNA1I | |
| SCHEMBL6246866 | 0.84 | KCNH2 (0.61) | KCNH2HTR4HTR3ACACNA1I | |
| SCHEMBL5779209 | 0.84 | HTR4 (0.79) | KCNH2HTR4HTR3A | |
| SCHEMBL6767167 | 0.83 | KCNH2 (0.62) | KCNH2HTR4HTR3A | |
| SCHEMBL5889899 | 0.83 | KCNH2 (0.62) | KCNH2HTR4HTR3ACACNA1I | |
| Oxalic Acid SCHEMBL6276898 | 0.83 | KCNH2 (0.65) | KCNH2HTR4HTR3ACACNA1I | |
| SCHEMBL6306539 | 0.83 | KCNH2 (0.61) | KCNH2HTR4HTR3ACACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951867-B2 | N-substituted piperidinyl-imidazopyridine compounds as 5-HT4 receptor modulators | PFIZER INC. (US) | 2005-10-04 | — | — | US | claimed |
| US-6951867-B2 | N-substituted piperidinyl-imidazopyridine compounds as 5-HT4 receptor modulators | PFIZER INC. (US) | 2005-10-04 | — | — | US | disclosed |