Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.90 |
| ▸ | F2 | P00734 | 17/20 | 0.90 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.90 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7458596 | 0.92 | F2 (0.75) | F10F2PRSS1 | |
| SCHEMBL7458603 | 0.90 | F10 (0.79) | F10F2PRSS1 | |
| SCHEMBL7363395 | 0.86 | F10 (0.83) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8345839 | 0.85 | F10 (0.87) | F10F2PRSS1 | |
| SCHEMBL8343396 | 0.81 | F10 (0.84) | F10F2PRSS1 | |
| SCHEMBL7454445 | 0.80 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL7457516 | 0.80 | F10 (0.82) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8343408 | 0.80 | F10 (0.89) | F10F2PRSS1 | |
| SCHEMBL7367197 | 0.79 | F2 (0.71) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8347821 | 0.79 | F10 (0.87) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |