Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858111 | 0.87 | RAB9A (0.78) | RAB9AALDH1A1NPC1MAPTHDAC1 | |
| SCHEMBL7060779 | 0.85 | RAB9A (0.66) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL4739925 | 0.79 | RAB9A (0.73) | RAB9AALDH1A1NPC1MAPTHDAC1 | |
| SCHEMBL1724937 | 0.79 | MAPT (0.67) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL1861725 | 0.79 | RAB9A (0.62) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL17281185 | 0.79 | RAB9A (0.58) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL9119580 | 0.79 | MAPT (0.71) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL5903862 | 0.78 | RAB9A (0.57) | RAB9AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL1861604 | 0.77 | HDAC1 (0.61) | RAB9AALDH1A1NPC1MAPTHDAC1 | |
| SCHEMBL5540068 | 0.77 | TSHR (0.61) | RAB9AALDH1A1NPC1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013130-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |