Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL6719239 | 0.94 | POLB (0.49) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL6718890 | 0.85 | RAB9A (0.53) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL6717651 | 0.81 | NPC1 (0.56) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL8347817 | 0.81 | NPC1 (0.56) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL6715814 | 0.81 | NPC1 (0.56) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL8344357 | 0.81 | NPC1 (0.60) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL8346804 | 0.81 | NPC1 (0.60) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL8396733 | 0.77 | MAPT (0.57) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL5186841 | 0.77 | MDM4 (0.67) | RAB9ANPC1POLBHPGDALDH1A1 | |
| SCHEMBL6718773 | 0.77 | RAB9A (0.55) | RAB9ANPC1POLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |