Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.43 |
| ▸ | CPB1 | P15086 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069460 | 0.88 | CDK5 (0.47) | CPB2CPB1LTA4HSIRT2 | |
| SCHEMBL6527840 | 0.88 | CDK5 (0.47) | CPB2CPB1LTA4HSIRT2 | |
| Hydrochloric Acid SCHEMBL6527843 | 0.87 | CDK5 (0.46) | CPB2CPB1LTA4HSIRT2 | |
| Hydrochloric Acid SCHEMBL5997862 | 0.87 | CDK5 (0.46) | CPB2CPB1LTA4HSIRT2 | |
| Hydrochloric Acid SCHEMBL6527838 | 0.87 | CDK5 (0.46) | CPB2CPB1LTA4HSIRT2 | |
| Hydrochloric Acid SCHEMBL7356305 | 0.87 | CDK5 (0.46) | CPB2CPB1LTA4HSIRT2 | |
| SCHEMBL6326552 | 0.87 | SLC7A5 (0.50) | CPB2CPB1 | |
| SCHEMBL8348975 | 0.83 | CPB2 (0.57) | CPB2CPB1 | |
| SCHEMBL8366596 | 0.81 | MEN1 (0.40) | CPB2CPB1SIRT2LPAR1MEN1 | |
| SCHEMBL8349095 | 0.81 | CPB2 (0.44) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003061653-A9 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LTD (GB) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003061653-A1 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |