SCHEMBL8345796

SCHEMBL8345796

C=CC(=O)OC(=O)C(=C)CC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
ALDH1A1 P00352 6/20 0.42
HPGD P15428 1/20 0.42
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 2/20 0.37
THRB P10828 3/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28854218 0.92 TSHR (0.37) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL22829694 0.85 TSHR (0.42) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL7520087 0.84 HCAR2 (0.37) TSHRALDH1A1HPGDNPSR1
SCHEMBL2438115 0.84 HCAR2 (0.37) TSHRALDH1A1HPGDNPSR1
SCHEMBL20840134 0.83 TSHR (0.39) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL5374418 0.82 TSHR (0.48) TSHRALDH1A1HPGDTP53CYP3A4
SCHEMBL19253760 0.82 TSHR (0.41) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL11876815 0.82 HCAR2 (0.35) TSHRALDH1A1NPSR1
Acrylic Acid Methyl Ester SCHEMBL17979227 0.81 TSHR (0.38) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL1061914 0.81 TSHR (0.47) TSHRALDH1A1HPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240100224-A1 TWO-FIELD COUPLING CROSSLINKED, INJECTABLE, MOLDABLE AND PRINTABLE GRANULAR HYDROGEL MATERIAL, PREPARATION METHOD THEREOF AND APPLICATION THEREOF DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2024-03-28 US claimed
CN-114788899-B Photocuring anti-adhesion gel and preparation method thereof 西安德诺海思医疗科技有限公司 2023-04-07 CN claimed
CN-115531290-A Tumor microenvironment acid response deep penetration nanogel and application thereof 深圳先进技术研究院 2022-12-30 CN claimed
CN-114788899-A Photocuring anti-adhesion gel and preparation method thereof 西安德诺海思医疗科技有限公司 2022-07-26 CN claimed
CN-113278168-A Two-field coupling cross-linked injectable plastic printable particle hydrogel material and preparation method and application thereof 大连理工大学 2021-08-20 CN claimed
EP-2914424-A1 TWO-PART PRIMER COMPOSITION Ashland Licensing And Intellectual Property, LLC (US) 2015-09-09 EP claimed
WO-2014070818-A1 TWO-PART PRIMER COMPOSITION ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2014-05-08 WO claimed
US-20140127499-A1 Two Part Primer Composition ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2014-05-08 US claimed
US-20240100224-A1 TWO-FIELD COUPLING CROSSLINKED, INJECTABLE, MOLDABLE AND PRINTABLE GRANULAR HYDROGEL MATERIAL, PREPARATION METHOD THEREOF AND APPLICATION THEREOF DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2024-03-28 US disclosed
CN-114788899-B Photocuring anti-adhesion gel and preparation method thereof 西安德诺海思医疗科技有限公司 2023-04-07 CN disclosed
CN-113278168-B Two-field coupling cross-linked injectable plastic printable particle hydrogel material and preparation method and application thereof 大连理工大学 2023-03-21 CN disclosed
CN-115531290-A Tumor microenvironment acid response deep penetration nanogel and application thereof 深圳先进技术研究院 2022-12-30 CN disclosed
CN-114788899-A Photocuring anti-adhesion gel and preparation method thereof 西安德诺海思医疗科技有限公司 2022-07-26 CN disclosed
CN-113278168-A Two-field coupling cross-linked injectable plastic printable particle hydrogel material and preparation method and application thereof 大连理工大学 2021-08-20 CN disclosed
US-5882828-A TONERS AND RESINS, DRYING TO REMOVE DISPERSION MEDIUM AND CONTACTING FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
US-5726728-A Liquid crystal display device and a production method utilizing surface free energies for the same SHARP KABUSHIKI KAISHA (JP) 1998-03-10 US disclosed
EP-0787160-A1 SILANE OLIGOMER AND RADIATION CURABLE COATING COMPOSITION CONTAINING THE OLIGOMER DSM N.V. (NL) 1997-08-06 EP disclosed
WO-1996012749-A1 SILANE OLIGOMER AND RADIATION CURABLE COATING COMPOSITION CONTAINING THE OLIGOMER DSM N.V. (NL) 1996-05-02 WO disclosed
US-4604342-A BINDER, PHOTOINITIATOR, AND ETHYLENICALLY UNSATURATED MONOMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-05 US disclosed
US-4308335-A MORDANT LAYER CONTAINING CATIONIC POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed