SCHEMBL7520087

SCHEMBL7520087

C=C(CC)C(=O)OC(=O)/C=C/C(=O)OC(=O)C(=C)CC

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.37
ATM Q13315 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALDH1A1 P00352 3/20 0.33
TSHR P16473 3/20 0.33
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2438115 1.00 HCAR2 (0.37) HCAR2ATMKEAP1NFE2L2ALDH1A1
SCHEMBL11876815 0.98 HCAR2 (0.35) HCAR2ATMKEAP1NFE2L2ALDH1A1
SCHEMBL27431596 0.92 HCAR2 (0.50) HCAR2ATMKEAP1NFE2L2ALDH1A1
Methacrylic Acid SCHEMBL5066930 0.90 HCAR2 (0.35) HCAR2ATMKEAP1NFE2L2ALDH1A1
SCHEMBL27711583 0.89 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL28123857 0.87
SCHEMBL8345796 0.84 TSHR (0.42) ALDH1A1TSHRNPSR1HPGD
SCHEMBL1898433 0.83 ATM (0.45) HCAR2ATMALDH1A1TSHRNPSR1
SCHEMBL1923846 0.82 ALDH1A1 (0.37) ATMALDH1A1TSHRNPSR1
Styrene SCHEMBL2816244 0.80 ALDH1A1 (0.42) HCAR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487084-B1 Image forming method and apparatus CANON KK (JP) 2002-01-30 EP disclosed
US-5864406-A Method and apparatus for forming halftone images on organic-silver-salt-based printing plates CANON KABUSHIKI KAISHA (JP) 1999-01-26 US disclosed
US-5529889-A CONTAINING CYANINE COMPOUND CANON KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed
EP-0559101-A1 Heat-developable photosensitive material and image forming method which uses the same CANON KABUSHIKI KAISHA (JP) 1993-09-08 EP disclosed
EP-0487084-A2 Image forming method and apparatus CANON KABUSHIKI KAISHA (JP) 1992-05-27 EP disclosed