Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253402 | 0.94 | LTA4H (0.44) | LTA4HTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL21218990 | 0.93 | TSHR (0.45) | LTA4HTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11318272 | 0.93 | TSHR (0.45) | LTA4HTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL27533862 | 0.93 | TSHR (0.45) | LTA4HTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11370317 | 0.93 | TSHR (0.45) | LTA4HTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6669566 | 0.83 | TDP1 (0.39) | TSHRTDP1CYP3A4ALDH1A1ESR1 | |
| SCHEMBL29130859 | 0.81 | TDP1 (0.43) | LTA4HTSHRTDP1L3MBTL1CYP1A2 | |
| SCHEMBL2938616 | 0.80 | LTA4H (0.47) | LTA4HTSHRTDP1L3MBTL1CYP1A2 | |
| SCHEMBL1726701 | 0.80 | LTA4H (0.47) | LTA4HTSHRTDP1L3MBTL1CYP1A2 | |
| SCHEMBL911477 | 0.79 | GAA (0.36) | LTA4HTSHRTDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990337-A | Process for the preparation of 2-cyanoethylphosphinic esters | TICONA GMBH (DE) | 1999-11-23 | — | — | US | claimed |
| US-10968241-B2 | Process for producing phosphinates | BASF SE (DE) | 2021-04-06 | — | — | US | disclosed |
| CN-108137629-B | Process for preparing phosphonites | 拜耳作物科学股份公司 | 2020-09-01 | — | — | CN | disclosed |
| US-20200079804-A1 | Process for producing phosphinates | BASF SE (DE) | 2020-03-12 | — | — | US | disclosed |
| EP-3356376-B1 | METHOD FOR THE PREPARATION OF PHOSPHINATES | BASF SE (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20180265529-A1 | PROCESS FOR PRODUCING PHOSPHINATES | BASF SE (DE) | 2018-09-20 | — | — | US | disclosed |
| CN-108137629-A | Process for preparing phosphonites | 拜耳作物科学股份公司 | 2018-06-08 | — | — | CN | disclosed |
| US-5990337-A | Process for the preparation of 2-cyanoethylphosphinic esters | TICONA GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5861107-A | ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| US-4613674-A | FIREPROOFING | TSOLIS ALEXANDROS K | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079804-A1 | Process for producing phosphinates | PTMS, PHOSPHO1, PPA1 | LTA4H 1509/4885TSHR 2690/4885TDP1 3099/4885 |
| US-10968241-B2 | Process for producing phosphinates | PTMS, PHOSPHO1, PPA1 | LTA4H 1509/4885TSHR 2690/4885TDP1 3099/4885 |
| US-20180265529-A1 | PROCESS FOR PRODUCING PHOSPHINATES | PTMS, PHOSPHO1, PPA1 | LTA4H 1509/4885TSHR 2690/4885TDP1 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.