Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27845351 | 0.98 | FOLH1 (0.40) | FOLH1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27490055 | 0.98 | TDP1 (0.42) | FOLH1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27832601 | 0.98 | TDP1 (0.42) | FOLH1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27519075 | 0.98 | FOLH1 (0.40) | FOLH1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27832599 | 0.98 | TDP1 (0.42) | FOLH1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL9777404 | 0.93 | TDP1 (0.43) | FOLH1LMNATDP1APEX1SMN1; SMN2 | |
| SCHEMBL42084 | 0.93 | TDP1 (0.43) | FOLH1LMNATDP1APEX1SMN1; SMN2 | |
| SCHEMBL10698543 | 0.93 | TDP1 (0.43) | FOLH1LMNATDP1APEX1SMN1; SMN2 | |
| SCHEMBL10698553 | 0.93 | TDP1 (0.43) | FOLH1LMNATDP1APEX1SMN1; SMN2 | |
| SCHEMBL987086 | 0.93 | TDP1 (0.43) | FOLH1LMNATDP1APEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769434-B | Air chain riveting glue and processing technology thereof | 广东远东高分子科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-108485563-A | A kind of water resistant adhesive pasted for environmental protection wall paper | 合肥浦尔菲电线科技有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-105131866-B | A kind of iron sheet panel composite surface aqueous adhesive and preparation method thereof | 顶立新材料科技有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-105592840-A | Cosmetic products | BASF SE | 2016-05-18 | — | — | CN | claimed |
| CN-105131866-A | Water-based adhesive for iron-sheet panel composite veneer and preparation method thereof | TAIZHOU DINGLI ADHESIVE CO LTD | 2015-12-09 | — | — | CN | claimed |
| CN-104169411-A | Water soluble compositions incorporating enzymes, and method of making same | MONOSOL LLC | 2014-11-26 | — | — | CN | claimed |
| CN-103987255-A | granular pesticide composition | NISSAN CHEMICAL IND LTD | 2014-08-13 | — | — | CN | claimed |
| CN-103958658-A | Cleaning compositions and methods | HONEYWELL INT INC | 2014-07-30 | — | — | CN | claimed |
| CN-103732063-A | Deodorization of peracids | ECOLAB USA INC | 2014-04-16 | — | — | CN | claimed |
| CN-103501596-A | Compositions and methods for improving physical stability of agricultural oil-based suspension formulations | HUNTSMAN CORP AUSTRALIA PTY LTD | 2014-01-08 | — | — | CN | claimed |
| CN-101052372-A | Zinc-containing dentifrice composition with improved taste | PROCTER & GAMBLE (US) | 2007-10-10 | — | — | CN | claimed |
| CN-101045406-A | Method for cleaning reversible thermosensitive recording medium, and image processing method | RICOH KK (JP) | 2007-10-03 | — | — | CN | claimed |
| CN-101039653-A | Solubilizing system for flavors and fragrances | FIRMENICH & CIE (CH) | 2007-09-19 | — | — | CN | claimed |
| CN-101040014-A | Recording ink, and ink cartridge, ink-recorded article, inkjet recording device and inkjet recording method | RICOH KK (JP) | 2007-09-19 | — | — | CN | claimed |
| CN-101031634-A | Non-chlorinated concentrated all-in-one acid detergent and method for using the same | DELAVAL HOLDING AB (SE) | 2007-09-05 | — | — | CN | claimed |
| CN-1701114-A | fabric care compositions for lipophilic fluid systems | PROCTER & GAMBLE (US) | 2005-11-23 | — | — | CN | claimed |
| CN-1533426-A | Liquid conditioner and method of laundering fabrics | — | 2004-09-29 | — | — | CN | claimed |
| CN-1501793-A | Improved skin composition | 荷兰联合利华有限公司 | 2004-06-02 | — | — | CN | claimed |
| CN-1070047-C | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 2001-08-29 | — | — | CN | claimed |
| CN-1231318-A | Biological degrading coating compositions | BAYER AG (DE) | 1999-10-13 | — | — | CN | claimed |