SCHEMBL987086

SCHEMBL987086

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nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.39
FOLH1 Q04609 3/20 0.36
GABRR1 P24046 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
SRC P12931 2/20 0.32
TSHR P16473 1/20 0.32
APEX1 P27695 1/20 0.31
CPA1 P15085 2/20 0.30
CPB1 P15086 1/20 0.30
CPA3 P15088 1/20 0.30
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42084 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10698540 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10698553 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL9777404 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL11360544 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10698543 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
Hydrogen Peroxide SCHEMBL28115963 1.00 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL7154950 0.97 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL2686163 0.97 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
Methane SCHEMBL9150719 0.97 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070027050-A1 Liquid cleansing composition CONOPCO, INC., D/B/A UNILEVER 2007-02-01 US claimed
US-20060183662-A1 Liquid cleansing composition with unique sensory properties UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-08-17 US claimed
US-20160128929-A1 METHOD FOR PRODUCTION OF STRUCTURED LIQUID COMPOSITIONS AND STRUCTURED LIQUID COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER 2016-05-12 US disclosed
EP-3007774-A1 METHOD FOR PRODUCTION OF STRUCTURED LIQUID COMPOSITIONS AND STRUCTURED LIQUID COMPOSITIONS UNILEVER N.V. (NL) 2016-04-20 EP disclosed
WO-2014207697-A2 AQUEOUS COSMETIC COMPOSITION IN FLEXIBLE SOLID FORM L'OREAL (FR) 2014-12-31 WO disclosed
WO-2014198496-A1 METHOD FOR PRODUCTION OF STRUCTURED LIQUID COMPOSITIONS AND STRUCTURED LIQUID COMPOSITIONS UNILEVER N.V. (NL) 2014-12-18 WO disclosed
EP-2356204-A2 SHAPED TOILET BARS Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-08-17 EP disclosed
EP-2195405-B1 MILD ACYL ISETHIONATE TOILET BAR COMPOSITION UNILEVER PLC (GB) 2011-03-09 EP disclosed
US-7867964-B2 manufactured via three dimensional cutting; characterized by specific surface profiles and topographic features CONOPCO, INC. (US) 2011-01-11 US disclosed
US-20070027050-A1 Liquid cleansing composition CONOPCO, INC., D/B/A UNILEVER 2007-02-01 US disclosed
US-20060183662-A1 Liquid cleansing composition with unique sensory properties UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-08-17 US disclosed
US-7015179-B1 Reduced odor toilet bar composition UNILEVER HOME & PERSONAL CARE USA (US) 2006-03-21 US disclosed
US-4680143-A DIALKYL SULFOSUCCINATE, SULFONATE, ALKYL ETHER SULFATE LEVER BROTHERS COMPANY (US) 1987-07-14 US disclosed
EP-0112045-B1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1987-01-21 EP disclosed
EP-0112044-B1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1986-10-01 EP disclosed
EP-0112047-B1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1986-09-24 EP disclosed
EP-0112047-A1 Detergent compositions UNILEVER N.V. (NL) 1984-06-27 EP disclosed
EP-0112045-A1 Detergent compositions UNILEVER N.V. (NL) 1984-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160128929-A1 METHOD FOR PRODUCTION OF STRUCTURED LIQUID COMPOSITIONS AND STRUCTURED LIQUID COMPOSITIONS CUTA, TAF5, TAF1 TDP1 736/4885SMN1; SMN2 1667/4885SLC22A6 2983/4885
US-20070027050-A1 Liquid cleansing composition CUTA, SPAST, DSG1 TDP1 2174/4885SMN1; SMN2 1285/4885SLC22A6 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.