Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089264 | 0.76 | PPARD (0.46) | PPARD | |
| SCHEMBL8345865 | 0.76 | BTN3A1 (0.32) | BTN3A1 | |
| SCHEMBL1876097 | 0.75 | BACE1 (0.31) | — | |
| SCHEMBL1549162 | 0.74 | PPARD (0.50) | PPARDFNTAFNTBPGGT1B | |
| SCHEMBL9360474 | 0.74 | TDP1 (0.38) | — | |
| SCHEMBL3928093 | 0.70 | PPARD (0.41) | PPARDFNTAFNTBPGGT1B | |
| SCHEMBL2142592 | 0.70 | — | — | |
| SCHEMBL9468147 | 0.69 | TDP1 (0.33) | — | |
| SCHEMBL28790081 | 0.69 | MAPT (0.31) | — | |
| SCHEMBL21379404 | 0.69 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939410-A | AN ANTIBIOTIC COMPRISING A HYDROLYSABLE ESTERS IN VIVO | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0831093-A1 | 1-Carba-(dethia)-Cephalosporin Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-03-25 | — | — | EP | disclosed |