Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713989 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL6714168 | 0.92 | MEN1 (0.56) | KMT2AALDH1A1MEN1NPSR1CYP2C9 | |
| SCHEMBL6714162 | 0.92 | MEN1 (0.56) | KMT2AALDH1A1MEN1NPSR1CYP2C9 | |
| SCHEMBL6718999 | 0.90 | MEN1 (0.43) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL8345944 | 0.90 | MEN1 (0.43) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL6718995 | 0.89 | MEN1 (0.45) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL6716681 | 0.85 | SMN1; SMN2 (0.55) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL6713993 | 0.81 | MAPT (0.48) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL6716241 | 0.77 | SMN1; SMN2 (0.55) | KMT2AALDH1A1MEN1LMNASMN1; SMN2 | |
| SCHEMBL6716665 | 0.77 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MEN1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |