Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718999 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6713989 | 0.90 | KMT2A (0.51) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8346261 | 0.90 | KMT2A (0.51) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6718995 | 0.88 | MEN1 (0.45) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6714162 | 0.88 | MEN1 (0.56) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6714168 | 0.88 | MEN1 (0.56) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6718673 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6717144 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6717245 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6716681 | 0.76 | SMN1; SMN2 (0.55) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |