Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LIPA | P38571 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418612 | 0.90 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL5348250 | 0.86 | — | — | |
| SCHEMBL29142824 | 0.80 | MAPT (0.62) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL16325497 | 0.79 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL28138013 | 0.79 | CYP19A1 (0.59) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL9646620 | 0.79 | NAAA (0.38) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL5354726 | 0.78 | NAAA (0.42) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL5348431 | 0.78 | NAAA (0.46) | HTTSMN1; SMN2KDM4ECYP19A1MAPT | |
| SCHEMBL9809370 | 0.77 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL3363236 | 0.77 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935563-A | SUNSCREEN AGENT; 3,5-DIALKYL SUBSTITUTED 4-HYDROXYBENZYLIDENECYANOACETATE DERIVATIVE USED AS A COSMETIC | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |