Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345591 | 0.87 | HTT (0.59) | FGFR1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL8343426 | 0.82 | FGFR1 (0.56) | FGFR1MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL8343437 | 0.82 | FGFR1 (0.51) | FGFR1MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8346813 | 0.80 | FGFR1 (0.47) | FGFR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL16158430 | 0.78 | FGFR1 (0.86) | FGFR1ALDH1A1HPGDHTTMAPK1 | |
| SCHEMBL8346864 | 0.77 | KMT2A (0.57) | MAPTALDH1A1HSD17B10HPGDCYP19A1 | |
| SCHEMBL8346599 | 0.77 | FGFR1 (0.60) | FGFR1MAPTALDH1A1LMNAPDE3B | |
| SCHEMBL8347592 | 0.77 | CYP19A1 (0.51) | FGFR1ALDH1A1CYP19A1PDE3BPDE3A | |
| SCHEMBL16158542 | 0.77 | FGFR1 (0.75) | FGFR1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL13900850 | 0.76 | FGFR1 (0.60) | FGFR1MAPTALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | disclosed |