Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341214 | 0.81 | ALDH1A1 (0.54) | FGFR1ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8343426 | 0.80 | FGFR1 (0.56) | FGFR1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL8346644 | 0.77 | FGFR1 (0.60) | FGFR1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL18674586 | 0.77 | SMN1; SMN2 (0.68) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL8346864 | 0.76 | KMT2A (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL2308773 | 0.76 | FGFR1 (1.00) | FGFR1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL29449347 | 0.76 | FGFR1 (1.00) | FGFR1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL8343140 | 0.73 | TUBB4A (0.53) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL25247614 | 0.73 | CSNK2A1 (0.62) | ALDH1A1MAPTRAB9ACSNK2A1MEN1 | |
| SCHEMBL426369 | 0.73 | MAPT (0.66) | ALDH1A1MAPTRAB9ACSNK2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | disclosed |