Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346992 | 1.00 | ELANE (0.47) | ELANEHSD17B10GAACYP1A2CYP2C9 | |
| SCHEMBL9803070 | 0.93 | ALOX5 (0.44) | ELANERAB9ASMN1; SMN2 | |
| SCHEMBL9724878 | 0.90 | HSD17B10 (0.58) | ELANEHSD17B10GAAKMT2AMAPT | |
| SCHEMBL9724876 | 0.90 | HSD17B10 (0.58) | ELANEHSD17B10GAAKMT2AMAPT | |
| SCHEMBL9802965 | 0.89 | ACACB (0.47) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL9803470 | 0.86 | ACACB (0.49) | CYP1A2CYP2C19L3MBTL1KMT2AMAPT | |
| SCHEMBL9803370 | 0.86 | RARB (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL9857232 | 0.85 | RXFP1 (0.43) | ELANEMEN1KMT2AMAPTRAB9A | |
| SCHEMBL11229156 | 0.84 | ELANE (0.50) | ELANEHSD17B10GAACYP1A2CYP2C9 | |
| SCHEMBL9802899 | 0.84 | RARB (0.55) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5989451-A | Compounds and methods for doping liquid crystal hosts | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1999-11-23 | — | — | US | disclosed |
| WO-1998034995-A1 | COMPOUNDS AND METHODS FOR DOPING LIQUID CRYSTAL HOSTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-08-13 | — | — | WO | disclosed |