SCHEMBL8347155

SCHEMBL8347155

C[C@@H]1[C@H](C)[C@@H]2CC(O)C[C@H]12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13451154 1.00 LMNA (0.35) LMNACYP2C9
SCHEMBL18177774 0.94 LMNA (0.32) LMNACYP2C9
SCHEMBL19272365 0.93
SCHEMBL18532862 0.93
SCHEMBL254575 0.71 LMNA (0.35) LMNACYP2C9
SCHEMBL21348884 0.71 LMNA (0.35) LMNACYP2C9
SCHEMBL18412782 0.71 LMNA (0.35) LMNACYP2C9
SCHEMBL11837106 0.71 LMNA (0.35) LMNACYP2C9
SCHEMBL17636101 0.71 LMNA (0.35) LMNACYP2C9
SCHEMBL13669534 0.71 LMNA (0.35) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379494-B1 FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS WARNER LAMBERT CO (US) 2010-03-10 EP disclosed
WO-2004016260-A1 THERAPEUTIC USE OF FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS PFIZER LIMITED (GB) 2004-02-26 WO disclosed