Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644631 | 0.85 | TSHR (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7628509 | 0.84 | TSHR (0.66) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1398528 | 0.84 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10579270 | 0.84 | TSHR (0.66) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11627412 | 0.83 | TSHR (0.69) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL31591535 | 0.81 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13397697 | 0.81 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL17995330 | 0.81 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL169664 | 0.81 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367616 | 0.80 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945491-A | Preparation of novel homo- and copolymers using atom transfer radical polymerization | CARNEGIE-MELLON UNIVERSITY (US) | 1999-08-31 | — | — | US | claimed |