Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717195 | 0.85 | MAPT (0.54) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6716834 | 0.85 | ALDH1A1 (0.56) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6715742 | 0.85 | NPC1 (0.56) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6713812 | 0.85 | ALDH1A1 (0.56) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6717232 | 0.84 | ALDH1A1 (0.53) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6717122 | 0.84 | MAPT (0.50) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6723832 | 0.84 | SMN1; SMN2 (0.54) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6717690 | 0.83 | POLB (0.47) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6716905 | 0.83 | KDM4E (0.58) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6713795 | 0.83 | ALDH1A1 (0.54) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |