Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348856 | 0.89 | HPGD (0.43) | HPGDHTR1AHTR7MAPK1NPSR1 | |
| SCHEMBL8349669 | 0.87 | HPGD (0.49) | HPGDHTR1AHTR7TSHRMAPT | |
| SCHEMBL8349639 | 0.86 | KMT2A (0.41) | TSHRALOX15MAPK1NPSR1ALDH1A1 | |
| SCHEMBL4947233 | 0.86 | HPGD (0.58) | HPGDHTR1AHTR7TSHRMAPT | |
| SCHEMBL8348259 | 0.86 | MEN1 (0.42) | HPGDMAPTALOX15MAPK1NPSR1 | |
| SCHEMBL4941241 | 0.84 | HPGD (0.54) | HPGDHTR1AHTR7TSHRMAPT | |
| SCHEMBL8349647 | 0.84 | HPGD (0.47) | HPGDHTR1AHTR7TSHRMAPT | |
| SCHEMBL4947228 | 0.83 | HPGD (0.55) | HPGDHTR1AHTR7TSHRMAPT | |
| SCHEMBL4945565 | 0.83 | HPGD (0.54) | HPGDTSHRMAPTHSD17B10ALOX15 | |
| SCHEMBL4942008 | 0.83 | HPGD (0.54) | HPGDTSHRMAPTHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053437-A1 | TRIAZOLES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |