Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PDE6D | O43924 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349639 | 0.90 | KMT2A (0.41) | MEN1KMT2AALDH1A1ALOX15MAPK1 | |
| SCHEMBL8346767 | 0.88 | ALDH1A1 (0.41) | MEN1KMT2AHPGDALDH1A1MAPK1 | |
| SCHEMBL8347347 | 0.86 | HPGD (0.47) | MEN1KMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL8349053 | 0.82 | MEN1 (0.42) | MEN1KMT2AHPGDATMALDH1A1 | |
| SCHEMBL8346474 | 0.82 | KMT2A (0.42) | MEN1KMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL4947206 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AHPGDATMALDH1A1 | |
| SCHEMBL4944189 | 0.80 | HPGD (0.48) | MEN1KMT2AHPGDATMALDH1A1 | |
| SCHEMBL4945525 | 0.80 | HPGD (0.48) | MEN1KMT2AHPGDATMALDH1A1 | |
| SCHEMBL8348963 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8349668 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053437-A1 | TRIAZOLES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |