Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 9/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.55 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.55 |
| ▸ | ACVR1B | P36896 | 5/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346014 | 0.91 | TGFBR1 (0.56) | BUB1NUDT1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL8346247 | 0.91 | TGFBR1 (0.59) | BUB1NUDT1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL5955139 | 0.90 | TGFBR1 (0.56) | BUB1NUDT1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL8347945 | 0.90 | BUB1 (0.58) | BUB1NUDT1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL8346119 | 0.90 | TGFBR1 (0.57) | BUB1NUDT1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL5955532 | 0.90 | TGFBR1 (0.59) | BUB1TGFBR1ACVRL1ACVR1BACVR1 | |
| SCHEMBL5954795 | 0.89 | TGFBR1 (0.58) | BUB1TGFBR1ACVRL1ACVR1BACVR1 | |
| SCHEMBL5954715 | 0.89 | TGFBR1 (0.58) | BUB1TGFBR1ACVRL1ACVR1BACVR1 | |
| SCHEMBL5954828 | 0.89 | TGFBR1 (0.60) | BUB1TGFBR1ACVRL1ACVR1BACVR1 | |
| SCHEMBL3827835 | 0.89 | TGFBR1 (0.59) | BUB1NUDT1TGFBR1ACVRL1ACVR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |