Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200023 | 0.89 | PTGDR2 (0.50) | TSHRSMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL18749637 | 0.85 | MRGPRX4 (0.49) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL18749785 | 0.84 | MRGPRX4 (0.48) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL13793923 | 0.84 | L3MBTL1 (0.51) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL8783048 | 0.83 | MRGPRX4 (0.50) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL8624560 | 0.81 | L3MBTL1 (0.49) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL17616657 | 0.79 | MRGPRX4 (0.51) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL16273717 | 0.79 | MRGPRX4 (0.61) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL18178868 | 0.78 | MRGPRX4 (0.50) | MRGPRX4FFAR4FFAR1L3MBTL1HPGD | |
| SCHEMBL7691906 | 0.78 | PTGDR2 (0.50) | HPGDTSHRSMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883250-A | ARYL SUBSTITUTED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| US-5679676-A | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |