Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327009 | 0.81 | RIPK1 (0.33) | — | |
| SCHEMBL13359975 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3TSHR | |
| SCHEMBL18250835 | 0.76 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12990820 | 0.76 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL13595065 | 0.75 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL28864982 | 0.74 | RECQL (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL11122133 | 0.72 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12757779 | 0.72 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL13345930 | 0.71 | CCNE1 (0.32) | MEN1KMT2A | |
| SCHEMBL12757777 | 0.71 | CCNE1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157489-B2 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-01-02 | — | — | US | disclosed |
| WO-2003078438-A1 | CARBAMATES AS HIV PROTEASE INHIBITORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-09-25 | — | — | WO | disclosed |