Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.86 |
| ▸ | ITGAV | P06756 | 20/20 | 0.86 |
| ▸ | ITGB6 | P18564 | 19/20 | 0.86 |
| ▸ | ITGB5 | P18084 | 14/20 | 0.86 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.86 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221711 | 1.00 | ITGB3 (0.86) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6223622 | 0.93 | ITGB3 (0.86) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6222815 | 0.92 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6223678 | 0.92 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6280654 | 0.90 | ITGB3 (0.70) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6221780 | 0.90 | ITGB3 (0.76) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6324794 | 0.89 | ITGB3 (0.89) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL21562753 | 0.88 | ITGB3 (0.92) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL20379586 | 0.88 | ITGB3 (0.92) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6218679 | 0.88 | ITGB3 (0.84) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058761-A1 | PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |