Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107966 | 0.84 | SNCA (0.56) | GAAPKMMAOB | |
| SCHEMBL4687827 | 0.83 | HTT (0.56) | GAAPKMTRPV1SLC22A6SLC22A8 | |
| SCHEMBL258201 | 0.83 | SMN1; SMN2 (0.58) | PKMTRPV1SLC22A6SLC22A8MEN1 | |
| SCHEMBL30675560 | 0.83 | SMN1; SMN2 (0.58) | PKMTRPV1SLC22A6SLC22A8MEN1 | |
| SCHEMBL8348359 | 0.83 | AURKB (0.64) | PKMSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL13886074 | 0.80 | TOP1 (0.50) | IMPDH2IMPDH1GAAPKMRAB9A | |
| SCHEMBL12058028 | 0.78 | SMN1; SMN2 (0.48) | IMPDH2IMPDH1GAAPKMTRPV1 | |
| SCHEMBL20679533 | 0.78 | CNR1 (0.55) | GAAPKMTRPV1SLC22A6SLC22A8 | |
| SCHEMBL30675606 | 0.78 | CNR1 (0.55) | GAAPKMTRPV1SLC22A6SLC22A8 | |
| SCHEMBL1381244 | 0.78 | TGM2 (0.59) | TRPV1CNR1CNR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101927-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER'S DISEASE, TYPE 2 DIABETES, AND PARKINSON'S DISEASE | PROTEOTECH, INC. (US) | 2003-12-11 | — | — | WO | disclosed |