Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 8/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31597716 | 0.83 | FABP6 (0.67) | PARP10PARP1FABP6PARP11APP | |
| SCHEMBL2983127 | 0.83 | FABP6 (0.67) | PARP10PARP1FABP6PARP11APP | |
| SCHEMBL14552660 | 0.80 | PARP10 (0.44) | PARP10PARP1FABP6PARP11APP | |
| SCHEMBL30646468 | 0.79 | FABP6 (0.45) | FABP6TGM2CES1TDP2 | |
| SCHEMBL13073090 | 0.79 | APP (0.38) | PARP10PARP1APPCYP19A1PBRM1 | |
| SCHEMBL13392166 | 0.75 | HPGD (0.43) | FABP6MAPTLMNA | |
| SCHEMBL22169027 | 0.75 | CYP19A1 (0.48) | PARP10PARP1FABP6CYP19A1MAPT | |
| SCHEMBL14470102 | 0.75 | PARP1 (0.48) | PARP1FABP6MAPTLMNAHTT | |
| SCHEMBL2171078 | 0.73 | PKM (0.50) | PARP10PARP1FABP6PARP11CYP19A1 | |
| SCHEMBL8469505 | 0.73 | MAPT (0.42) | APPCYP19A1PBRM1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014880-A1 | CHROMONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |