Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717157 | 0.86 | ALDH1A1 (0.56) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6713795 | 0.86 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6715692 | 0.84 | MEN1 (0.55) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6716681 | 0.82 | SMN1; SMN2 (0.55) | LMNAALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL6718673 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1HPGDMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6717144 | 0.81 | ALDH1A1 (0.46) | LMNAALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8344236 | 0.81 | MEN1 (0.46) | ALDH1A1MEN1KMT2ARECQLALOX12 | |
| SCHEMBL6723754 | 0.79 | ALDH1A1 (0.57) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6717668 | 0.79 | MEN1 (0.54) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6713812 | 0.78 | ALDH1A1 (0.56) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |