Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348255 | 0.98 | HRH1 (0.50) | HRH1CXCR4CYP2A6PDPK1MAOA | |
| SCHEMBL4773757 | 0.92 | CYP2A6 (0.48) | HRH1CXCR4CYP2A6PDPK1 | |
| SCHEMBL8346110 | 0.84 | HRH1 (0.47) | HRH1CXCR4CYP2A6 | |
| SCHEMBL27550187 | 0.84 | TDP1 (0.47) | CXCR4PDPK1TLR8 | |
| SCHEMBL5748952 | 0.84 | TDP1 (0.47) | CXCR4PDPK1TLR8 | |
| SCHEMBL5745538 | 0.84 | TDP1 (0.47) | CXCR4PDPK1TLR8 | |
| SCHEMBL5746124 | 0.84 | TDP1 (0.47) | CXCR4PDPK1TLR8 | |
| SCHEMBL27524862 | 0.84 | TDP1 (0.47) | CXCR4PDPK1TLR8 | |
| SCHEMBL5369216 | 0.81 | TDP1 (0.49) | CXCR4PDPK1TLR8 | |
| SCHEMBL11218925 | 0.79 | HRH1 (0.50) | HRH1CXCR4CYP2A6PDPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |