Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14559586 | 1.00 | KMT2A (0.35) | KMT2AALDH1A1MAPTCYP2D6L3MBTL1 | |
| SCHEMBL8347235 | 1.00 | KMT2A (0.35) | KMT2AALDH1A1MAPTCYP2D6L3MBTL1 | |
| SCHEMBL14599665 | 0.97 | ALDH1A1 (0.33) | KMT2AALDH1A1MAPTL3MBTL1MGAM | |
| SCHEMBL14559592 | 0.97 | ALDH1A1 (0.33) | KMT2AALDH1A1MAPTL3MBTL1MGAM | |
| SCHEMBL14559595 | 0.97 | ALDH1A1 (0.33) | KMT2AALDH1A1MAPTL3MBTL1MGAM | |
| SCHEMBL8345214 | 0.94 | KMT2A (0.33) | KMT2AALDH1A1MAPTL3MBTL1MGAM | |
| SCHEMBL14559623 | 0.94 | KMT2A (0.33) | KMT2AALDH1A1MAPTL3MBTL1MGAM | |
| SCHEMBL5080768 | 0.84 | MGAM (0.34) | KMT2AALDH1A1L3MBTL1MGAMGAA | |
| SCHEMBL5690613 | 0.84 | MGAM (0.34) | KMT2AALDH1A1L3MBTL1MGAMGAA | |
| SCHEMBL5077870 | 0.84 | MGAM (0.34) | KMT2AALDH1A1L3MBTL1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189747-B2 | Method of treating noninflammatory cartilage damage | WARNER-LAMBERT COMPANY (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189747-B2 | Method of treating noninflammatory cartilage damage | WARNER-LAMBERT COMPANY (US) | 2007-03-13 | — | — | US | disclosed |
| WO-2003063845-A1 | ALPHA 2 DELTA LIGANDS TO TREAT TINNITUS | WARNER-LAMBERT COMPANY LLC (US) | 2003-08-07 | — | — | WO | disclosed |