Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.62 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 8/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942351 | 0.89 | CTSK (0.79) | CTSKCTSSCCR1 | |
| SCHEMBL5942356 | 0.89 | CTSK (0.79) | CTSKCTSSCCR1 | |
| SCHEMBL4039281 | 0.89 | CTSK (0.79) | CTSKCTSSCCR1 | |
| SCHEMBL4045666 | 0.81 | CTSK (0.67) | CTSKCTSSCCR1 | |
| SCHEMBL4042583 | 0.78 | CTSK (0.73) | CTSKPREPCTSSALDH1A1HPGD | |
| SCHEMBL4038274 | 0.78 | CTSK (0.65) | CTSKCTSSCCR1 | |
| SCHEMBL4041441 | 0.78 | CTSK (0.79) | CTSKCTSSALDH1A1KMT2ACCR1 | |
| SCHEMBL4042162 | 0.77 | CTSK (0.63) | CTSKCTSS | |
| SCHEMBL4207941 | 0.76 | CTSK (0.87) | CTSKCTSSALDH1A1HPGDKMT2A | |
| SCHEMBL4219737 | 0.76 | CTSK (1.00) | CTSKCTSSALDH1A1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |