Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44393 | 0.87 | ATM (0.70) | KDM4EATMCA2MAPK1KMT2A | |
| SCHEMBL29535675 | 0.87 | ATM (0.70) | KDM4EATMCA2MAPK1KMT2A | |
| SCHEMBL19409880 | 0.87 | ATM (0.70) | KDM4EATMCA2MAPK1KMT2A | |
| SCHEMBL506373 | 0.85 | CSNK2A1 (0.66) | KDM4EATMCSNK2A1CA2MEN1 | |
| SCHEMBL29673212 | 0.85 | CSNK2A1 (0.51) | KDM4EATMCSNK2A1CA2LMNA | |
| SCHEMBL559310 | 0.85 | CSNK2A1 (0.51) | KDM4EATMCSNK2A1CA2LMNA | |
| Hydrochloric Acid SCHEMBL9726669 | 0.85 | ATM (0.68) | KDM4EATMCSNK2A1CA2LMNA | |
| Hydrochloric Acid SCHEMBL8299478 | 0.84 | CSNK2A1 (0.53) | KDM4EATMCSNK2A1CA2LMNA | |
| Hydrochloric Acid SCHEMBL856874 | 0.84 | CSNK2A1 (0.67) | KDM4EATMCSNK2A1LMNAMEN1 | |
| SCHEMBL8349187 | 0.81 | LMNA (0.62) | KDM4ECA2LMNACLK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031506-A9 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | LILLY CO ELI (US) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999031507-A1 | PEPTIDOMIMETIC TEMPLATE-BASED COMBINATORIAL LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031506-A1 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |